Rs4680

id: rs4680-311-16400397
title: Rs4680
text: In genetics, rs4680 (Val158Met) is a genetic variant. It is a single nucleotide polymorphism (SNP) in the COMT gene that codes catechol-O-Methyltransferase. The single nucleotide substitution between G--> A results in an amino acid change from valine to methionine at codon 158. The A or Met allele is associated with lower enzymatic activity, and with exploratory behaviour. The polymorphism has been much studied in schizophrenia research but as of November 2011 meta-analysis in the SzGene databas
brand slug: wiki
category slug: encyclopedia
description: Genetic variant
original url: https://en.wikipedia.org/wiki/Rs4680
date created:
date modified: 2023-09-09T04:27:48Z
main entity: {"identifier":"Q17142059","url":"https://www.wikidata.org/entity/Q17142059"}
image:
fields total: 13
integrity: 14

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