RS134-49
id:
rs134-49-186-10418455
title:
RS134-49
text:
RS134-49 is a tetrahydropyridine derivative related to psychedelic tryptamines which acts as a 5-HT2A receptor agonist, with a 5-HT2A Ki of 11.5nM and an EC50 of 22nM. It is a biased agonist selective for activation of the Gq coupled signalling pathway with weaker activation of the β-arrestin 2 coupled pathway, but shows a more balanced profile than related compounds such as (R)-69.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/RS134-49
date created:
2024-03-01T07:36:45Z
date modified:
2024-09-08T03:25:06Z
main entity:
{"identifier":"Q124854103","url":"https://www.wikidata.org/entity/Q124854103"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/d7/RS134-49_structure.png","width":873,"height":833}
fields total:
13
integrity:
16