RNF216

id: rnf216-297-242100
title: RNF216
text: E3 ubiquitin-protein ligase RNF216 is an enzyme that in humans is encoded by the RNF216 gene. This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accep
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/RNF216
date created:
date modified: 2023-03-04T00:01:07Z
main entity: {"identifier":"Q18041033","url":"https://www.wikidata.org/entity/Q18041033"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/99/Ideogram_human_chromosome_7.svg","width":474,"height":189}
fields total: 13
integrity: 15

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