Ribonucleoprotein Networks Analyzed by Mutational Profiling

id: ribonucleoprotein-networks-analyzed-by-mutational-profiling-310-1131382
title: Ribonucleoprotein Networks Analyzed by Mutational Profiling
text: Ribonucleoprotein Networks Analyzed by Mutational Profiling (RNP-MaP) is a strategy for probing RNA-protein networks and protein binding sites at a nucleotide resolution. Information about RNP assembly and function can facilitate a better understanding of biological mechanisms. RNP-MaP uses NHS-diazirine (SDA), a hetero-bifunctional crosslinker, to freeze RNA-bound proteins in place. Once the RNA-protein crosslinks are formed, MaP reverse transcription is then conducted to reversely transcribe t
brand slug: wiki
category slug: encyclopedia
description: Protein-RNA binding probing method
original url: https://en.wikipedia.org/wiki/Ribonucleoprotein_Networks_Analyzed_by_Mutational_Profiling
date created:
date modified: 2024-02-22T12:16:54Z
main entity: {"identifier":"Q112958113","url":"https://www.wikidata.org/entity/Q112958113"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/eb/RNP-MaP_workflow.png","width":720,"height":504}
fields total: 13
integrity: 15

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