Reverse pharmacology
id:
reverse-pharmacology-266-4378729
title:
Reverse pharmacology
text:
In the field of drug discovery, reverse pharmacology also known as target-based drug discovery (TDD), a hypothesis is first made that modulation of the activity of a specific protein target thought to be disease modifying will have beneficial therapeutic effects. Screening of chemical libraries of small molecules is then used to identify compounds that bind with high affinity to the target. The hits from these screens are then used as starting points for drug discovery. This method became popula
brand slug:
wiki
category slug:
encyclopedia
description:
Drug discovery by identifying protein targets
original url:
https://en.wikipedia.org/wiki/Reverse_pharmacology
date created:
date modified:
2023-12-03T12:49:47Z
main entity:
{"identifier":"Q7318256","url":"https://www.wikidata.org/entity/Q7318256"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/82/Forward_and_reverse_pharmacology.jpg","width":602,"height":491}
fields total:
13
integrity:
15