RepSox
id:
repsox-292-2525284
title:
RepSox
text:
RepSox is a small molecule inhibitor of TGFβR1, also known as ALK5, that was first identified in the wake of the discovery of the Yamanaka factors. It has shown promise in a variety of in-vitro and in-vivo rodent trials modelling various diseases. It inhibits TGFβR1 autophosphorylation by preventing the protein from binding with ATP, inhibits the binding of TGF-β to TGFβR1, and prevents the transcription of genes activated by TGFβR1 with nanomolar potency. RepSox is a member of the 1,5-naphthyri
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/RepSox
date created:
date modified:
2024-01-23T11:12:30Z
main entity:
{"identifier":"Q72506526","url":"https://www.wikidata.org/entity/Q72506526"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/45/RepSox_Skeletal_Structure.png","width":1925,"height":1378}
fields total:
13
integrity:
15