REL
id:
rel-309-12238415
title:
REL
text:
The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. The c-Rel protein is a member of the NF-κB family of transcription factors and contains a Rel homology domain (RHD) at its N-terminus and two C-terminal transactivation domains. c-Rel is a myeloid checkpoint protein that can be targeted for treating cancer. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several human B-cell lymphomas, including diffuse large
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/REL
date created:
date modified:
2022-10-12T00:58:23Z
main entity:
{"identifier":"Q18031085","url":"https://www.wikidata.org/entity/Q18031085"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/aa/Ideogram_human_chromosome_2.svg","width":474,"height":189}
fields total:
13
integrity:
15