Regulation of transcription in cancer
id:
regulation-of-transcription-in-cancer-294-8334141
title:
Regulation of transcription in cancer
text:
Generally, in progression to cancer, hundreds of genes are silenced or activated. Although silencing of some genes in cancers occurs by mutation, a large proportion of carcinogenic gene silencing is a result of altered DNA methylation. DNA methylation causing silencing in cancer typically occurs at multiple CpG sites in the CpG islands that are present in the promoters of protein coding genes. Altered expressions of microRNAs also silence or activate many genes in progression to cancer. Altered
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Regulation_of_transcription_in_cancer
date created:
date modified:
2023-12-03T22:58:23Z
main entity:
{"identifier":"Q28209440","url":"https://www.wikidata.org/entity/Q28209440"}
image:
fields total:
13
integrity:
13