Reformatsky reaction
id:
reformatsky-reaction-200-161621
title:
Reformatsky reaction
text:
The Reformatsky reaction is an organic reaction which condenses aldehydes or ketones with α-halo esters using metallic zinc to form β-hydroxy-esters: The organozinc reagent, also called a 'Reformatsky enolate', is prepared by treating an alpha-halo ester with zinc dust. Reformatsky enolates are less reactive than lithium enolates or Grignard reagents and hence nucleophilic addition to the ester group does not occur. The reaction was discovered by Sergey Nikolaevich Reformatsky. Some reviews have
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wiki
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encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Reformatsky_reaction
date created:
date modified:
2023-10-31T19:55:58Z
main entity:
{"identifier":"Q898948","url":"https://www.wikidata.org/entity/Q898948"}
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13
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