Recombinant AAV mediated genome engineering
id:
recombinant-aav-mediated-genome-engineering-283-2648015
title:
Recombinant AAV mediated genome engineering
text:
Recombinant adeno-associated virus (rAAV) based genome engineering is a genome editing platform centered on the use of recombinant AAV vectors that enables insertion, deletion or substitution of DNA sequences into the genomes of live mammalian cells. The technique builds on Mario Capecchi and Oliver Smithies' Nobel Prize–winning discovery that homologous recombination (HR), a natural hi-fidelity DNA repair mechanism, can be harnessed to perform precise genome alterations in mice. rAAV mediated g
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Recombinant_AAV_mediated_genome_engineering
date created:
date modified:
2023-12-03T01:29:30Z
main entity:
{"identifier":"Q17077643","url":"https://www.wikidata.org/entity/Q17077643"}
image:
fields total:
13
integrity:
13