Reactive nitrogen species

id: reactive-nitrogen-species-200-4078848
title: Reactive nitrogen species
text: Reactive nitrogen species (RNS) are a family of antimicrobial molecules derived from nitric oxide (•NO) and superoxide (O2•−) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively. NOS2 is expressed primarily in macrophages after induction by cytokines and microbial products, notably interferon-gamma (IFN-γ) and lipopolysaccharide (LPS). Reactive nitrogen species act together with reactive oxygen species (ROS) to damage cells, causing nitr
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Reactive_nitrogen_species
date created:
date modified: 2024-01-27T06:24:13Z
main entity: {"identifier":"Q225595","url":"https://www.wikidata.org/entity/Q225595"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/62/Reactions_leading_to_generation_of_Nitric_Oxide_and_Reactive_Nitrogen_Species.jpg","width":1200,"height":1591}
fields total: 13
integrity: 14

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