R13 (drug)
id:
r13-drug-305-14893001
title:
R13 (drug)
text:
R13 is a small-molecule flavonoid and orally active, potent, and selective agonist of the tropomyosin receptor kinase B (TrkB) – the main signaling receptor for the neurotrophin brain-derived neurotrophic factor (BDNF) – which is under development for the potential treatment of Alzheimer's disease. It is a structural modification and prodrug of tropoflavin (7,8-DHF) with improved potency and pharmacokinetics, namely oral bioavailability and duration. The compound is a replacement for the earlier
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/R13_(drug)
date created:
date modified:
2023-12-03T13:14:52Z
main entity:
{"identifier":"Q55283856","url":"https://www.wikidata.org/entity/Q55283856"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e2/R13.svg","width":697,"height":467}
fields total:
13
integrity:
15