R-spondin 2
id:
r-spondin-2-260-199652
title:
R-spondin 2
text:
R-spondin 2 also known as roof plate-specific spondin-2 is a secreted protein that in humans that is encoded by the RSPO2 gene. R-spondin 2 synergizes with canonical WNT to activate beta-catenin. RSPO2 has been proposed to regulate craniofacial patterning and morphogenesis within pharyngeal arch 1 through ectoderm-mesenchyme signaling via the endothelin-Dlx5/6 pathway. In dogs, a variant on the Rspo2 gene is associated moustache and eyebrow thickness. In humans, recessive mutations in RSPO2 abro
brand slug:
wiki
category slug:
encyclopedia
description:
Protein and coding gene in humans
original url:
https://en.wikipedia.org/wiki/R-spondin_2
date created:
date modified:
2023-06-22T05:12:47Z
main entity:
{"identifier":"Q18055407","url":"https://www.wikidata.org/entity/Q18055407"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/60/Ideogram_human_chromosome_8.svg","width":474,"height":189}
fields total:
13
integrity:
15