Pyruvate kinase PKLR
id:
pyruvate-kinase-pklr-291-11215020
title:
Pyruvate kinase PKLR
text:
Pyruvate kinase PKLR is an enzyme that in humans is encoded by the PKLR gene. The protein encoded by this gene is a pyruvate kinase that catalyzes the production of pyruvate and ATP from phosphoenolpyruvate. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia. Alternatively spliced transcript variants encoding distinct isoforms have been described.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Pyruvate_kinase_PKLR
date created:
date modified:
2024-04-10T22:02:47Z
main entity:
{"identifier":"Q18030566","url":"https://www.wikidata.org/entity/Q18030566"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/0b/Protein_PKLR_PDB_1liu.png","width":973,"height":786}
fields total:
13
integrity:
15