PYR-41

id: pyr-41-318-6366924
title: PYR-41
text: PYR-41 is a cell permeable irreversible inhibitor of ubiquitin-activating enzyme E1. It was also reported to increase sumoylation in cells. PYR-41 also blocks the downstream ubiquitination and ubiquitination-dependent protein degradation or other ubiquitination-mediated cellular activities. In addition, PYR-41 inhibits degradation of p53, a tumour suppressor.
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/PYR-41
date created:
date modified: 2022-08-19T13:41:32Z
main entity: {"identifier":"Q18385814","url":"https://www.wikidata.org/entity/Q18385814"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/83/PYR-41.svg","width":512,"height":289}
fields total: 13
integrity: 15

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