PVSRIPO
id:
pvsripo-263-14750141
title:
PVSRIPO
text:
PVSRIPO, or PVS-RIPO, is the name of a modified polio virus that has recently shown promise for treating cancer. It is the focus of clinical trials being conducted at Duke University. PVS-RIPO consists of a genetically modified nonpathogenic version of the oral poliovirus Sabin type 1. The internal ribosome entry site (IRES) on the poliovirus was replaced with the IRES from human rhinovirus type 2 (HRV2), to avoid neurovirulence. Once administered, the virus enters and begins replicating within
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/PVSRIPO
date created:
date modified:
2023-12-12T10:31:12Z
main entity:
{"identifier":"Q20026902","url":"https://www.wikidata.org/entity/Q20026902"}
image:
fields total:
13
integrity:
13