Pudovik reaction

id: pudovik-reaction-308-5500176
title: Pudovik reaction
text: In organophosphorus chemistry, the Pudovik reaction is a method for preparing α-aminomethylphosphonates. Under basic conditions, the phosphorus–hydrogen bond of a dialkylphosphite, (RO)2P(O)H, adds across the carbon–nitrogen double bond of an imine (a hydrophosphonylation reaction). The reaction is closely related to the three-component Kabachnik–Fields reaction, where an amine, phosphite, and an organic carbonyl compound are condensed, which was reported independently by Martin Kabachnik and El
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original url: https://en.wikipedia.org/wiki/Pudovik_reaction
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date modified: 2024-01-05T19:12:47Z
main entity: {"identifier":"Q48996360","url":"https://www.wikidata.org/entity/Q48996360"}
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