PSB-10
id:
psb-10-302-11572514
title:
PSB-10
text:
PSB-10 is a drug which acts as a selective antagonist for the adenosine A3 receptor (ki value at human A3 receptor is 0.44 nM), with high selectivity over the other three adenosine receptor subtypes (ki values at human A1, A2A and A2B receptors are 4.1, 3.3 and 30 μM). Further pharmacological experiments in a [35S]GTPγS binding assay using hA3-CHO-cells indicated that PSB-10 acts as an inverse agonist (IC50 = 4 nM). It has been shown to produce antiinflammatory effects in animal studies. Simple
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/PSB-10
date created:
date modified:
2024-02-04T01:38:38Z
main entity:
{"identifier":"Q7120601","url":"https://www.wikidata.org/entity/Q7120601"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/db/PSB-10.svg","width":512,"height":307}
fields total:
13
integrity:
15