PRX-08066

id: prx-08066-274-8196373
title: PRX-08066
text: PRX-08066 is a drug discovered and developed by Predix Pharmaceuticals [Dale S. Dhanoa et al. Patent US 7,030,240 B2], which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with a 5-HT2B binding affinity (Ki) of 3.4nM, and high selectivity over the closely related 5-HT2A and 5-HT2C receptors and other receptor targets. PRX-08066 and other selective 5-HT2B antagonists are being researched for the treatment of pulmonary arterial hypertension, following the discovery tha
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/PRX-08066
date created:
date modified: 2023-12-06T01:01:14Z
main entity: {"identifier":"Q44793","url":"https://www.wikidata.org/entity/Q44793"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/a3/PRX-08066_structure.png","width":824,"height":454}
fields total: 13
integrity: 15

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