Proadifen

id: proadifen-309-9231005
title: Proadifen
text: Proadifen (SKF-525A) is a non-selective inhibitor of cytochrome P450 enzymes, preventing some types of drug metabolism. It is also an inhibitor of neuronal nitric oxide synthase (NOS), CYP-dependent arachidonate metabolism, transmembrane calcium influx, and platelet thromboxane synthesis. Further documented effects include the blockade of ATP-sensitive inward rectifier potassium channel 8 (KIR6.1), and stimulation of endothelial cell prostacyclin production. Proadifen exerts apoptotic/anti-proli
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Proadifen
date created:
date modified: 2023-12-20T16:17:42Z
main entity: {"identifier":"Q7246819","url":"https://www.wikidata.org/entity/Q7246819"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/1f/Proadifen.png","width":1057,"height":574}
fields total: 13
integrity: 15

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