Prickle (protein)
id:
prickle-protein-290-6543726
title:
Prickle (protein)
text:
Prickle is also known as REST/NRSF-interacting LIM domain protein, which is a putative nuclear translocation receptor. Prickle is part of the non-canonical Wnt signaling pathway that establishes planar cell polarity. A gain or loss of function of Prickle1 causes defects in the convergent extension movements of gastrulation. In epithelial cells, Prickle2 establishes and maintains cell apical/basal polarity. Prickle1 plays an important role in the development of the nervous system by regulating th
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Prickle_(protein)
date created:
date modified:
2023-02-03T06:35:28Z
main entity:
{"identifier":"Q7242693","url":"https://www.wikidata.org/entity/Q7242693"}
image:
fields total:
13
integrity:
13