Presenilin-1
id:
presenilin-1-249-16015677
title:
Presenilin-1
text:
Presenilin-1 (PS-1) is a presenilin protein that in humans is encoded by the PSEN1 gene. Presenilin-1 is one of the four core proteins in the gamma secretase complex, which is considered to play an important role in generation of amyloid beta (Aβ) from amyloid-beta precursor protein (APP). Accumulation of amyloid beta is associated with the onset of Alzheimer's disease.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Presenilin-1
date created:
date modified:
2023-12-31T11:23:17Z
main entity:
{"identifier":"Q18253272","url":"https://www.wikidata.org/entity/Q18253272"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/78/Ideogram_human_chromosome_14.svg","width":474,"height":189}
fields total:
13
integrity:
15