Pr/set domain 15
id:
pr-set-domain-15-295-13914836
title:
Pr/set domain 15
text:
PR/SET domain 15 is a protein that in humans is encoded by the PRDM15 gene. PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling. PRDM15 modulates WNT and MAPK/ERK signaling by directly promoting the expression of Rspo1 (R-spondin1) and Spry1 (Sprouty1). Mzoughi et al., have shown that PRDM15 binds to the promoter region of both genes, inducing changes in the local chromatin to promote their transcription. In a second report, the same team has identifie
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/Pr/set_domain_15
date created:
date modified:
2024-04-09T22:02:12Z
main entity:
{"identifier":"Q18045528","url":"https://www.wikidata.org/entity/Q18045528"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/c/c1/Ideogram_human_chromosome_21.svg","width":474,"height":189}
fields total:
13
integrity:
15