Polynucleotide phosphorylase

id: polynucleotide-phosphorylase-297-16482262
title: Polynucleotide phosphorylase
text: Polynucleotide Phosphorylase (PNPase) is a bifunctional enzyme with a phosphorolytic 3' to 5' exoribonuclease activity and a 3'-terminal oligonucleotide polymerase activity. That is, it dismantles the RNA chain starting at the 3' end and working toward the 5' end. It also synthesizes long, highly heteropolymeric tails in vivo. It accounts for all of the observed residual polyadenylation in strains of Escherichia coli missing the normal polyadenylation enzyme. Discovered by Marianne Grunberg-Mana
brand slug: wiki
category slug: encyclopedia
description: Class of enzymes
original url: https://en.wikipedia.org/wiki/Polynucleotide_phosphorylase
date created:
date modified: 2023-12-01T01:00:57Z
main entity: {"identifier":"Q24780839","url":"https://www.wikidata.org/entity/Q24780839"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/83/Crystal_structure_1E3P.jpg","width":500,"height":500}
fields total: 13
integrity: 15

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