Polynucleotide 5'-hydroxyl-kinase

id: polynucleotide-5-hydroxyl-kinase-295-16007523
title: Polynucleotide 5'-hydroxyl-kinase
text: In enzymology, a polynucleotide 5'-hydroxyl-kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and 5'-dephospho-DNA, whereas its two products are ADP and 5'-phospho-DNA. Polynucleotide kinase is a T7 bacteriophage enzyme that catalyzes the transfer of a gamma-phosphate from ATP to the free hydroxyl end of the 5' DNA or RNA. The resulting product could be used to end-label DNA or RNA, or in ligation reactions.
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Polynucleotide_5%27-hydroxyl-kinase
date created:
date modified: 2023-08-26T15:30:09Z
main entity: {"identifier":"Q7226659","url":"https://www.wikidata.org/entity/Q7226659"}
image:
fields total: 13
integrity: 13

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