PNU-99,194
id:
pnu-99-194-248-14790883
title:
PNU-99,194
text:
PNU-99,194(A) (or U-99,194(A)) is a drug which acts as a moderately selective D3 receptor antagonist with ~15-30-fold preference for D3 over the D2 subtype. Though it has substantially greater preference for D3 over D2, the latter receptor does still play some role in its effects, as evidenced by the fact that PNU-99,194 weakly stimulates both prolactin secretion and striatal dopamine synthesis, actions it does not share with the more selective (100-fold) D3 receptor antagonists S-14,297 and GR-
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/PNU-99,194
date created:
date modified:
2022-12-27T15:44:22Z
main entity:
{"identifier":"Q7119895","url":"https://www.wikidata.org/entity/Q7119895"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/ac/PNU-99194A-structure.png","width":1849,"height":1026}
fields total:
13
integrity:
15