Pleckstrin homology domain

id: pleckstrin-homology-domain-205-5759421
title: Pleckstrin homology domain
text: Pleckstrin homology domain or (PHIP) is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton. This domain can bind phosphatidylinositol lipids within biological membranes, and proteins such as the βγ-subunits of heterotrimeric G proteins, and protein kinase C. Through these interactions, PH domains play a role in recruiting proteins to different membranes, thus targeting them to approp
brand slug: wiki
category slug: encyclopedia
description: Protein domain
original url: https://en.wikipedia.org/wiki/Pleckstrin_homology_domain
date created: 2006-03-06T08:30:48Z
date modified: 2024-09-10T10:27:01Z
main entity: {"identifier":"Q24776397","url":"https://www.wikidata.org/entity/Q24776397"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/8f/1bwn_opm.png","width":829,"height":669}
fields total: 13
integrity: 16

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