Pivaloyloxymethyl
id:
pivaloyloxymethyl-202-6991815
title:
Pivaloyloxymethyl
text:
Pivaloyloxymethyl (POM, pivoxil, pivoxyl) is a protecting group used in organic synthesis. The POM radical has the formula (CH3)3C-CO-O-CH2. The POM group is also sometimes used to produce prodrugs. For example, the POM group can be attached to a negatively charged organophosphate group(s) of a drug causing a neutralization of the negative charge, which can allow the drug to become more lipid-soluble and thus more able to diffuse passively across cell membranes into cells. Upon entry into cells,
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Pivaloyloxymethyl
date created:
date modified:
2023-11-28T23:50:13Z
main entity:
{"identifier":"Q7199625","url":"https://www.wikidata.org/entity/Q7199625"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b5/Pivaloyloxymethyl.svg","width":512,"height":303}
fields total:
13
integrity:
14