Photochemical internalization
id:
photochemical-internalization-253-15849085
title:
Photochemical internalization
text:
Photochemical internalization (PCI) is a drug and gene therapy delivery method originally developed to improve the release of macromolecules and hydrophilic chemotherapeutic agents from endosomes and lysosomes to the cytosol of targeted cancer cells. PCI is based on the use of endosomal and lysosomal localizing amphiphilic photosensitizers which, after activation by light, induce photochemical reactions resulting in destruction of endocytic membranes mediated by reactive oxygen species (ROS). Th
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Photochemical_internalization
date created:
date modified:
2023-12-18T05:20:58Z
main entity:
{"identifier":"Q17773791","url":"https://www.wikidata.org/entity/Q17773791"}
image:
fields total:
13
integrity:
13