Phosphonium coupling
id:
phosphonium-coupling-264-408758
title:
Phosphonium coupling
text:
In organic chemistry, phosphonium coupling is a cross-coupling reaction for organic synthesis. It is a mild, efficient, chemoselective and versatile methodology for the formation of C–C, C–N, C–O, and C–S bond of unactivated and unprotected tautomerizable heterocycles. The method was originally reported in 2004. The C–OH bond of a tautomerizable heterocycle is activated with a phosphonium salt, and subsequent functionalization with either a nucleophile through SNAr displacement or an organometal
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wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Phosphonium_coupling
date created:
date modified:
2022-08-26T00:36:40Z
main entity:
{"identifier":"Q7187528","url":"https://www.wikidata.org/entity/Q7187528"}
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fields total:
13
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13