Pelger–Huët anomaly
id:
pelger-hu-t-anomaly-171-7587254
title:
Pelger–Huët anomaly
text:
Pelger–Huët anomaly is a blood laminopathy associated with the lamin B receptor, wherein several types of white blood cells have nuclei with unusual shape and unusual structure. It is a genetic disorder with an autosomal dominant inheritance pattern. Heterozygotes are clinically normal, although their neutrophils may be mistaken for immature cells which may cause mistreatment in a clinical setting. Homozygotes tend to have neutrophils with rounded nuclei that do have some functional problems.
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Pelger%E2%80%93Hu%C3%ABt_anomaly
date created:
2007-09-29T20:01:56Z
date modified:
2024-09-01T05:28:59Z
main entity:
{"identifier":"Q975182","url":"https://www.wikidata.org/entity/Q975182"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/02/Hypogranular_neutrophil_with_a_pseudo-Pelger-Huet_nucleus_in_MDS.jpg","width":359,"height":512}
fields total:
13
integrity:
16