Peak-to-trough ratio
id:
peak-to-trough-ratio-292-453756
title:
Peak-to-trough ratio
text:
Peak-to-trough ratio (PTR), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of Cmax (peak) concentration and Cmin (trough) concentration over a dosing interval for a given drug. A drug with an elimination half-life of 24 hours taken once per day will have a peak-to-trough ratio of approximately 2. Peak-to-trough ratio is proportional to half-life and to dosing interval, with longer half-lives and shorter dosin
brand slug:
wiki
category slug:
encyclopedia
description:
Pharmacokinetic metrics
original url:
https://en.wikipedia.org/wiki/Peak-to-trough_ratio
date created:
date modified:
2022-03-31T06:03:04Z
main entity:
{"identifier":"Q109255360","url":"https://www.wikidata.org/entity/Q109255360"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/ee/Linear_PK_Example.png","width":1600,"height":1118}
fields total:
13
integrity:
15