Paradoxical disinhibition
id:
paradoxical-disinhibition-306-2731366
title:
Paradoxical disinhibition
text:
Paradoxical disinhibition is a paradoxical reaction, an uncommon but recognized phenomenon, characterized by acute excitement and an altered mental state, caused by benzodiazepines. The mechanism is poorly known, but the most accepted theory is that it occurs secondary
to inhibition of the restraining influences of the cortex and frontal lobe due to the GABA-mimetic action of benzodiazepines. Reversal of this action could be attained by an NMDA-receptor antagonist, ketamine.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Paradoxical_disinhibition
date created:
date modified:
2021-12-09T17:03:38Z
main entity:
{"identifier":"Q7134467","url":"https://www.wikidata.org/entity/Q7134467"}
image:
fields total:
13
integrity:
13