PAR-CLIP

id: par-clip-248-6610209
title: PAR-CLIP
text: PAR-CLIP is a biochemical method for identifying the binding sites of cellular RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs). The method relies on the incorporation of ribonucleoside analogs that are photoreactive, such as 4-thiouridine (4-SU) and 6-thioguanosine (6-SG), into nascent RNA transcripts by living cells. Irradiation of the cells by ultraviolet light of 365 nm wavelength induces efficient crosslinking of photoreactive nucleoside–labeled cellu
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/PAR-CLIP
date created:
date modified: 2023-12-03T03:20:53Z
main entity: {"identifier":"Q7118193","url":"https://www.wikidata.org/entity/Q7118193"}
image:
fields total: 13
integrity: 13

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