Pan-assay interference compounds
id:
pan-assay-interference-compounds-296-11333982
title:
Pan-assay interference compounds
text:
Pan-assay interference compounds (PAINS) are chemical compounds that often give false positive results in high-throughput screens. PAINS tend to react nonspecifically with numerous biological targets rather than specifically affecting one desired target. A number of disruptive functional groups are shared by many PAINS. While a number of filters have been proposed and are used in virtual screening and computer-aided drug design, the accuracy of filters with regard to compounds they flag and don'
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Pan-assay_interference_compounds
date created:
date modified:
2023-10-31T11:10:09Z
main entity:
{"identifier":"Q25101047","url":"https://www.wikidata.org/entity/Q25101047"}
image:
fields total:
13
integrity:
13