P-ANCA
id:
p-anca-262-11415206
title:
P-ANCA
text:
p-ANCA, or MPO-ANCA, or perinuclear anti-neutrophil cytoplasmic antibodies, are antibodies that stain the material around the nucleus of a neutrophil. They are a special class of anti-neutrophil cytoplasmic antibodies. This pattern occurs because the vast majority of the antigens targeted by ANCAs are highly cationic at pH 7.00. During ethanol fixation, antigens which are more cationic migrate and localize around the nucleus, attracted by its negatively charged DNA content. Antibody staining the
brand slug:
wiki
category slug:
encyclopedia
description:
Type of autoantibody
original url:
https://en.wikipedia.org/wiki/P-ANCA
date created:
date modified:
2024-02-28T21:42:05Z
main entity:
{"identifier":"Q7116884","url":"https://www.wikidata.org/entity/Q7116884"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/90/P_anca.jpg","width":347,"height":343}
fields total:
13
integrity:
15