Ormdl sphingolipid biosynthesis regulator 3
id:
ormdl-sphingolipid-biosynthesis-regulator-3-289-4135209
title:
Ormdl sphingolipid biosynthesis regulator 3
text:
ORMDL sphingolipid biosynthesis regulator 3 is a protein that in humans is encoded by the ORMDL3 gene. Variants affecting the expression of this gene are associated with asthma in childhood. Transgenic mice which overexpress human ORMDL3 have increased levels of IgE. This correlated with increased numbers of macrophages, neutrophils, eosinophils, CD4+ and enhanced Th2 cytokine levels in the lung tissue.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Ormdl_sphingolipid_biosynthesis_regulator_3
date created:
date modified:
2024-04-07T23:08:20Z
main entity:
{"identifier":"Q18048785","url":"https://www.wikidata.org/entity/Q18048785"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/00/Ideogram_human_chromosome_17.svg","width":474,"height":189}
fields total:
13
integrity:
15