Olney's lesions
id:
olney-s-lesions-172-8316788
title:
Olney's lesions
text:
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor. NMDA antagonism is common in anesthesia, as well as certain psychiatric treatments. The visible signs of NAT are named after John Olney, who conducted
brand slug:
wiki
category slug:
encyclopedia
description:
Neurotoxicity caused by some NMDA receptor antagonists
original url:
https://en.wikipedia.org/wiki/Olney%27s_lesions
date created:
2005-01-29T02:16:10Z
date modified:
2024-09-02T06:35:41Z
main entity:
{"identifier":"Q2657006","url":"https://www.wikidata.org/entity/Q2657006"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/c/c7/Fnana-07-00023-g002.jpg","width":546,"height":546}
fields total:
13
integrity:
16