NUMB (gene)
id:
numb-gene-278-12953935
title:
NUMB (gene)
text:
Protein numb homolog is a protein that in humans is encoded by the NUMB gene. The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. The protein Numb is coded for by the gene, NUMB, whose
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/NUMB_(gene)
date created:
date modified:
2024-04-06T23:50:37Z
main entity:
{"identifier":"Q18033185","url":"https://www.wikidata.org/entity/Q18033185"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/2d/Protein_NUMB_PDB_1wj1.png","width":690,"height":486}
fields total:
13
integrity:
15