Nozaki–Hiyama–Kishi reaction
id:
nozaki-hiyama-kishi-reaction-264-3803870
title:
Nozaki–Hiyama–Kishi reaction
text:
The Nozaki–Hiyama–Kishi reaction is a nickel/chromium coupling reaction forming an alcohol from the reaction of an aldehyde with an allyl or vinyl halide. In their original 1977 publication, Tamejiro Hiyama and Hitoshi Nozaki reported on a chromium(II) salt solution prepared by reduction of chromic chloride by lithium aluminium hydride to which was added benzaldehyde and allyl chloride: Compared to Grignard reactions, this reaction is very selective towards aldehydes with large tolerance towards
brand slug:
wiki
category slug:
encyclopedia
description:
Coupling reaction used in organic synthesis
original url:
https://en.wikipedia.org/wiki/Nozaki%E2%80%93Hiyama%E2%80%93Kishi_reaction
date created:
date modified:
2023-01-24T16:24:16Z
main entity:
{"identifier":"Q903204","url":"https://www.wikidata.org/entity/Q903204"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/ab/Nozaki1986.svg","width":396,"height":190}
fields total:
13
integrity:
15