Nortilidine

id: nortilidine-293-13701454
title: Nortilidine
text: Nortilidine is the major active metabolite of tilidine. It is formed from tilidine by demethylation in the liver. The racemate has opioid analgesic effects roughly equivalent in potency to that of morphine. The (1R,2S) isomer has NMDA antagonist activity. The drug also acts as a dopamine reuptake inhibitor. The reversed-ester of nortilidine is also known, as is the corresponding analogue with the cyclohexene ring replaced by cyclopentane, which have almost identical properties to nortilidine.
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Nortilidine
date created:
date modified: 2022-04-16T08:54:45Z
main entity: {"identifier":"Q12746349","url":"https://www.wikidata.org/entity/Q12746349"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5b/Nortilidine.svg","width":1088,"height":944}
fields total: 13
integrity: 15

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