Noroxycodone
id:
noroxycodone-247-5738870
title:
Noroxycodone
text:
Noroxycodone is the major metabolite of the opioid analgesic oxycodone. It is formed from oxycodone in the liver via N-demethylation predominantly by CYP3A4. Noroxycodone binds to and activates the μ-opioid receptor (MOR) similarly to oxycodone, although with one-third of the affinity of oxycodone and 5- to 10-fold lower activational potency. However, although a potent MOR agonist, noroxycodone poorly crosses the blood-brain-barrier into the central nervous system, and for this reason, is only m
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Noroxycodone
date created:
date modified:
2024-02-08T14:45:15Z
main entity:
{"identifier":"Q27271817","url":"https://www.wikidata.org/entity/Q27271817"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/66/Noroxycodone.svg","width":865,"height":880}
fields total:
13
integrity:
15