Non-stop decay

id: non-stop-decay-292-17507825
title: Non-stop decay
text: Non-stop decay (NSD) is a cellular mechanism of mRNA surveillance to detect mRNA molecules lacking a stop codon and prevent these mRNAs from translation. The non-stop decay pathway releases ribosomes that have reached the far 3' end of an mRNA and guides the mRNA to the exosome complex, or to RNase R in bacteria for selective degradation. In contrast to nonsense-mediated decay (NMD), polypeptides do not release from the ribosome, and thus, NSD seems to involve mRNA decay factors distinct from NM
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Non-stop_decay
date created:
date modified: 2023-06-10T04:04:59Z
main entity: {"identifier":"Q16944825","url":"https://www.wikidata.org/entity/Q16944825"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/07/Nonstopdecay.jpg","width":658,"height":656}
fields total: 13
integrity: 14

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