Non-homologous end-joining factor 1
id:
non-homologous-end-joining-factor-1-234-15775200
title:
Non-homologous end-joining factor 1
text:
Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene. XLF was originally discovered as the protein mutated in five patients with growth retardation, microcephaly, and immunodeficiency. The protein is required for the non-homologous end joining (NHEJ) pathway of DNA repair. Patients with XLF mutations also have immunodeficiency due to a defect in V(D)J recombination, which uses NHEJ to generate di
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Non-homologous_end-joining_factor_1
date created:
date modified:
2023-11-07T12:24:25Z
main entity:
{"identifier":"Q18046396","url":"https://www.wikidata.org/entity/Q18046396"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/dc/Protein_NHEJ1_PDB_2QM4.png","width":1200,"height":1000}
fields total:
13
integrity:
15