Neocarzinostatin
id:
neocarzinostatin-264-1699368
title:
Neocarzinostatin
text:
Neocarzinostatin (NCS) is a macromolecular chromoprotein enediyne antitumor antibiotic secreted by Streptomyces macromomyceticus. It consists of two parts, a labile chromophore and a 113 amino acid protein to which the chromophore is tightly and non-covalently bound with high affinity. The non-protein component is a very potent DNA-damaging agent; However it is extremely unstable and the role of the protein is to protect it and release it to the target DNA. Opening of the epoxide under reductive
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Neocarzinostatin
date created:
date modified:
2024-03-17T06:48:57Z
main entity:
{"identifier":"Q205145","url":"https://www.wikidata.org/entity/Q205145"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/71/Neocarzinostatin.png","width":868,"height":823}
fields total:
13
integrity:
15