NEDD4
id:
nedd4-198-3813941
title:
NEDD4
text:
E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 is an enzyme that is, in humans, encoded by the NEDD4 gene. NEDD4 is an E3 ubiquitin ligase enzyme, that targets proteins for ubiquitination. NEDD4 is, in eukaryotes, a highly conserved gene, and the founding member of the NEDD4 family of E3 HECT ubiquitin ligases, which in humans consists of 9 members: NEDD4
NEDD4-2
ITCH
SMURF1
SMURF2
WWP1
WWP2
NEDL1 (HECW1)
NEDDL2 (HECW2)].
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/NEDD4
date created:
date modified:
2024-03-27T21:44:44Z
main entity:
{"identifier":"Q18030005","url":"https://www.wikidata.org/entity/Q18030005"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/29/NEDD4_HECT_domain_structure_from_PDB_ID_2XBF.png","width":1050,"height":850}
fields total:
13
integrity:
15