N-Desmethyltamoxifen
id:
n-desmethyltamoxifen-200-12497415
title:
N-Desmethyltamoxifen
text:
N-Desmethyltamoxifen is a major metabolite of tamoxifen, a selective estrogen receptor modulator (SERM). N-Desmethyltamoxifen is further metabolized into endoxifen (4-hydroxy-N-desmethyltamoxifen), which is thought to be the major active form of tamoxifen in the body. In one study, N-desmethyltamoxifen had an affinity for the estrogen receptor of 2.4% relative to estradiol. For comparison, tamoxifen, endoxifen, and afimoxifene (4-hydroxytamoxifen) had relative binding affinities of 2.8%, 181%, a
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/N-Desmethyltamoxifen
date created:
date modified:
2022-03-05T22:33:35Z
main entity:
{"identifier":"Q27149597","url":"https://www.wikidata.org/entity/Q27149597"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/80/N-Desmethyltamoxifen-skeletal.svg","width":1110,"height":770}
fields total:
13
integrity:
15