Myeloma cast nephropathy
id:
myeloma-cast-nephropathy-246-1726395
title:
Myeloma cast nephropathy
text:
Myeloma cast nephropathy, also referred to as light-chain cast nephropathy, is the formation of plugs in the kidney tubules from free immunoglobulin light chains leading to kidney failure in the context of multiple myeloma. It is the most common cause of kidney injury in myeloma. In myeloma cast nephropathy, filtered κ or λ light chains that bind to Tamm-Horsfall protein precipitate in the kidney's tubules. Hypercalcemia and low fluid intake contribute to the development of casts. Myeloma cast n
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Myeloma_cast_nephropathy
date created:
date modified:
2024-02-11T23:03:10Z
main entity:
{"identifier":"Q1956557","url":"https://www.wikidata.org/entity/Q1956557"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/fc/Cast_nephropathy_-_2_cropped_-_very_high_mag.jpg","width":2848,"height":2136}
fields total:
13
integrity:
15