Mydicar
id:
mydicar-247-13482160
title:
Mydicar
text:
Mydicar is a genetically targeted enzyme replacement therapy being studied for use in patients with severe heart failure. It is designed to increase the level of SERCA2a, a sarcoplasmic endoplasmic reticulum calcium (Ca2+) ATPase found in the membrane of the sarcoplasmic reticulum (SR). The SERCA2a gene is delivered to the heart via an adeno-associated viral vector. Using the α-myosin heavy chain gene promoter in the cardiac muscle cells, also called cardiomyocytes, Mydicar is able to direct the
brand slug:
wiki
category slug:
encyclopedia
description:
Genetically targeted enzyme replacement therapy
original url:
https://en.wikipedia.org/wiki/Mydicar
date created:
date modified:
2021-10-29T17:03:19Z
main entity:
{"identifier":"Q6947268","url":"https://www.wikidata.org/entity/Q6947268"}
image:
fields total:
13
integrity:
14