MUTYH-associated polyposis
id:
mutyh-associated-polyposis-272-13246764
title:
MUTYH-associated polyposis
text:
MUTYH-associated polyposis is an autosomal recessive polyposis syndrome. The disorder is caused by mutations in both alleles of the DNA repair gene, MUTYH. The MUTYH gene encodes a base excision repair protein, which corrects oxidative damage to DNA. Affected individuals have an increased risk of colorectal cancer, precancerous colon polyps (adenomas) and an increased risk of several additional cancers. About 1–2 percent of the population possess a mutated copy of the MUTYH gene, and less than 1
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/MUTYH-associated_polyposis
date created:
date modified:
2024-01-30T21:43:58Z
main entity:
{"identifier":"Q1266575","url":"https://www.wikidata.org/entity/Q1266575"}
image:
fields total:
13
integrity:
14